Calcium d-glucarate, I find that many people can benefit from a supplement that not many people even know exists.

 

This vitamin is…

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Calcium D-glucarate. 

This supplement is a safe form of a calcium salt derived from d-glucaric acid.  You can find this derivative in various fruits and vegetables, and it is made in small quantities in our bodies.   It is present in the following foods: apples, apricots, citrus fruits, cherries, grapefruits, broccoli, Brussels sprouts, and alfalfa sprouts.

Calcium D-glucarate is readily absorbed, active in small doses and bioavailable in the body for relatively extended periods of time with many health benefits. Let’s talk a look at some of the known advantages of this phytonutrient.

Counteracts Intestinal Inflammation

The truth is that many of us have large amounts of inflammation in our guts that is not treated properly or addressed at all.  This is due to genetics, poor diets, digestive imbalances, food sensitivities, and infections.  The digestive system is the foundation of good health and many of us are struggling (and many of us don’t even know that are guts are struggling).

When there is an imbalance in the digestive system, one of the byproducts that occur with an increase in harmful bacteria or a low level of good bacteria is something called beta-glucuronidase.  Calcium d-glucarate has a direct effect on this byproduct and therefore, can help to counteract intestinal imbalance.  By calcium d-glucarate inhibiting the effects of beta-glucuronidase, the body can then more efficiently remove toxins and balance the gut.

Liver and cellular detoxifier

Calcium d-glucarate helps with detoxification through a few different mechanisms.  It supports the liver and detox pathways.  With this, it also helps hormone balance since hormones have to be broken down by the liver.

Since it also is a beta-glucuronidase inhibitor, this also helps to support the liver.  By inhibiting this toxic byproduct of beta-glucuronidase, the excretion of toxic molecules through the detoxification pathway is promoted.   Therefore, calcium d-glucurate has been shownin various studies to boost the body’s capacity to eliminate toxins and waste products while balancing hormones.

Estrogen metabolizer

There are now numerous estrogen mimickers in our environment.  These are wrecking havoc on our hormones, mood, and waistlines in both men and women.

Calcium d-glucarate works by metabolizing an excess of estrogen in the body and helps the liver to metabolize hormones which is necessary for both males and females.  Increased estrogen will interfere with testosterone in men and lead to severe hormone imbalances in women.  It is incredibly vital to balance hormones for overall health and wellness and so hard because of all the environmental foreign mimickers.  Calcium d-glucarate accomplishes this difficult task by fortifying the liver and detoxifying unwanted hormones.

Therefore, it helps to protect the body against hormone mimickers, such as plastics, eliminates toxins and wastes from the body, and regulates hormone levels.

 

Lipid-lowering agent

Decreasing the byproduct of beta-glucuronidase from gut production increases liver circulation and reduces cholesterol synthesis.  Both of these effects helps to lower total and LDL cholesterol.

Decrease the possibility of cancer

We know without a doubt that a diet high in fruits and vegetables has many benefits and helps to decrease the chance of certain degenerative diseases and cancers.  This is due to many reasons including phytonutrients that are in fruits and vegetables.  One of these compounds is calcium d-glucarate.  It does this by suppressing cell proliferation that we see in cancer situations and also reduces chronic inflammation by decreasing the level of inflammatory cytokines in the body.

Research shows that it lowers cancer risks.  So much so that the AMC Cancer Research enter even recommends calcium d-glucarate.

Even though there are so many benefits to this supplement, it is not possible to get the amounts of glucaric acid that are necessary to thrive from food alone and humans produce only small levels of calcium d-glucarate.  Back in the day, these small amounts of natural glucaric acid was enough when we lived in an environment with low toxins and ate a clean and natural diet.  But, unfortunately, we now live in an environment where we need additional support against toxins and hormone mimickers.

Therefore, we need supplementation at a higher dose. The research recommends to take at least 200-400 mg/day.  It is also okay to go for a higher dose because it is a natural substance and essentially nontoxic.  Most research shows that the therapeutic dose is closer to the 1500-3000 mg/day.

I like to actually utilize calcium d-glucarate with other supplements to help balance hormones and detoxify through multiply pathways.  My favorite supplements to balance hormone levels are calcium d-glucarate, DIM, Indole-3-carbionol and green tea extract.

Everyone truly can benefit from calcium d-glucarate.  This supplement is especially excellent for hormonal imbalances, infertility concerns, detox programs, and I highly recommended for bodybuilders to help support their overall health and physique in conjunction with good diet and exercise program.

Article by Dr. Meaghan Kirschling, DC, APRN, RN, MS
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